De-Larve

De-Larve is an insect growth regulator whose active ingredient is Diflubenzeron 25%. The dispersible powder disrupts the moulting process of mosquito larvae for the Anopheles, Aedes and Culex species of mosquitoes, and controls Malaria, Dengue and other vector-borne diseases.

Approvals

World Health Organization – Diflubenzuron was classified by WHO (1992) as “a product unlikely to present an acute hazard in normal use” (based on acute oral LD50 for rat greater than 4640 mg/kg body weight). In “Environmental Health Criteria” N 184/96, WHO classified Diflubenzuron as a product with very low or reversible effects on most aquatic non-target organisms. WHO approved Diflubenzuron for use even in drinking water. 

Central Insecticide Board India – De-Larve has been approved by the Central Insecticide Board, Ministry of Agriculture, Government of India. 

National Vector Borne Disease Control Program – De-Larve is recommended by the National Vector Borne Disease Control Program (NVBDCP), Ministry of Health and Family Welfare, Government of India for use in vector-control programs throughout the country.

Salient Features

Effective & efficient – The use of De-Larve is an efficient approach to the control of mosquito larvae, and is more effective than control strategies for adult mosquitoes.  

Works on resistant mosquitoes – Disrupting the moulting process works effectively on mosquito larvae that might have developed some resistance to other chemical larvicides.  

Safety – De-Larve is more effective in smaller doses and is also safer for the user and the environment than other insecticides. Easily applied by hand operated spray pumps, it is stable even in high temperatures (with a flash point of 110 ºC).  

Cost effective – It is cost-effective and fit for use in both potable and polluted water.

Broad spectrum usage – De-Larve is extremely effective against all types of mosquitoes: Aedes, Anopheles and Culex. It controls Malaria, Dengue and other vector borne diseases.

Mode of Action

Insect larvae synthesize Chitin, which is required for the formation of their cuticle (outer covering). When these larvae ingest or come in contact with De-Larve, the chitin synthesis is inhibited and the cuticle does not form properly. As a result, the muscles involved in the moulting process do not find proper attachment to the malformed new cuticle. The weakened cuticle ruptures easily leading to an exudation of body fluid. This deviation from the normal moulting process ultimately leads to deformation and death of the larvae.